Calcium Metabolism and Bone Changes in Sarcoidosis
نویسندگان
چکیده
منابع مشابه
Clinical impact of bone and calcium metabolism changes in sarcoidosis.
Even before the introduction of X-rays, Besnier had noted the association of swelling of the fingers with lupus pernio. In 1904 Karl Kreibich, later Professor of Dermatology in Prague but at that time working in Vienna, described four patients with cystic changes in the bones of the hand in connection with lupus pernio and gave an excellent radiographic reproduction of the hands in one and sarc...
متن کاملCalcium Metabolism in Sarcoidosis.
Fifteen patients with hypercalcaemia and sarcoidosis have been studied. Twelve were males of average age 34; the three females averaged 53. Cases included widely varying sarcoid manifestations , but five gave a clear history of rather excessive ingestion of low-dosage vitamin D preparations. The data confirm that in most cases there is an undue sensitivity to all the actions of vitamin D, the s...
متن کاملCalcium and vitamin D metabolism in sarcoidosis.
BACKGROUND Sarcoidosis associated hypercalcemia (SAHC) may be secondary to excessive levels of 1,25-(OH)2 vitamin D3 produced by autonomous 1-alpha-hydroxylase activity within the granulomas. The frequency, treatment, and consequences of hypercalcemia remain unclear. STUDY DESIGN AND METHODS Two patient cohorts were studied. In Cohort 1, the prevalence of hypercalcemia in 1606 sarcoidosis p...
متن کاملFrequency of disordered calcium metabolism in sarcoidosis.
A prospective study of total and ultrafiltrable serum calcium levels in 121 patients with sarcoidosis and thirty-eight control subjects revealed no significant differences. Two patients had hypercalcaemia (11-6 and 12-2 mg%) at the time of initial sampling; one spontaneously returned to normal. Retrospective analysis of 318 cases previously studied demonstrated persistent hypercalcaemia in eigh...
متن کاملStrontium and Calcium Metabolism in Metabolic Bone
Skeletal and systemic disease may be reflected in profound alterations of the metabolism of the bone salts. In human skeletal disease attention has focused, for the most part, on the altered metabolism of calcium. Several studies indicate that strontium may have a metabolic pathway similar to that of calcium and that radiostrontium, because of its ease of measurement, might be a convenient indi...
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ژورنال
عنوان ژورنال: BMJ
سال: 1957
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.1.5013.248